A major score-rigging scandal has engulfed one of Tokyo's medical schools, with an investigation revealing the university deliberately marked down all female applicants to limit the number of women studying at the school.

It is understood the senior officials at Tokyo Medical University wanted to keep the number of women at about 30
per cent, so they altered the computerised marking system.

The practice had reportedly been going on for more than a decade.

University officials said they would now "sincerely" consider their response, including the possibility of compensation, but they maintained they were unaware of the manipulation.