In the midst of one of the largest HIV outbreaks in Indigenous Queenslanders, over $740,000 has been withdrawn from a HIV drug trial by the Queensland Government.

Cairns, Cape York, and the Torres Strait are among the worst affected regions, with 41 cases being recorded since 2014.

A sexual health expert indicated the 1,400 men coming off the trial will put pressure onto clinics in the short time frame with the HIV treatment now requiring a prescription.