Brisbane's busiest rail stations south of Roma Street will shut down over the Christmas period to allow for a $56 million signalling upgrade.

The upgrades are planned for the line between Roma Street and Corinda, with all trains stopped between Saturday, December 22, and Saturday, December 29.

Queensland Rail chief executive Nick Easy says the installations will "future-proof" the rail lines and reduce the need for future maintenance.

Queensland Rail is working with TransLink to ensure additional buses required will not affect normal bus routes and travellers will not be inconvenienced.