New heart health research has revealed parts of Queensland and outback Northern Territory are worst impacted by the disease.

Heart foundation general manager of heart health and research, Bill Stavreski, told Sky News that a high prevalence of smoking, physical inactivity and difficulty in accessing medical services from remote areas were significant contributors.

Cardiovascular disease is a major cause of death in Australia, with 43,500 deaths attributed to CVD in Australia in 2017.