The Bureau of Meteorology is forecasting a heatwave will affect most of Victoria and will bring stuffy overnight temperatures on Friday and Saturday.

The Chief Health Officer has issued a heat health alert for Victorians in the central district from Thursday through to Saturday, warning that the elderly, children and those with pre-existing medical conditions are most at risk.

Emergency Management Victoria warned fire danger ratings will likely increase to severe in some areas on Saturday, with temperatures tipped to reach up to 40 degrees.

The Emergency Management Commissioner reminded the public to stay hydrated, while Yarra Trams is changing certain route services in light of the heatwave, which may bring longer commute times.