Queensland's former chief scientist is possibly facing jail time for defrauding the government of about $75,000.

Suzanne Miller pleaded guilty in Brisbane Magistrates Court on Thursday to committing fraud during her time employed by the Queensland Museum between February 2014 and July 2017.

She was first charged in 2017, by the Crime and Corruption Commission with fraud valued about $45,000 relating to a false claim for private health insurance.

Ms Miller was charged again later that year over the alleged misuse of a state government- funded credit card to buy herself items costing more than $30,000.

These items included a polaroid camera, pink LED lights, a drone, a Gold Smart scooter and a high-pressure cleaner, according to court documents.

Her guilty plea on Thursday was to a single charge of fraud, after dozens of allegations were rolled into one.